Sid Meier scores another hit w/ Civilization Revolution All versions support multiplayer games for up to four over an internet connection.Īntigua and Barbuda, Aruba, Australia, Austria, Bahamas, Bahrain, Bangladesh, Barbados, Belgium, Belize, Bermuda, Bolivia, Brazil, Brunei Darussalam, Bulgaria, Cambodia, Canada, Cayman Islands, Chile, Colombia, Costa Rica, Croatia, Republic of, Cyprus, Czech Republic, Denmark, Dominica, Dominican Republic, Ecuador, Egypt, El Salvador, Estonia, Finland, France, French Guiana, Germany, Gibraltar, Greece, Grenada, Guadeloupe, Guatemala, Guernsey, Honduras, Hungary, Iceland, Indonesia, Ireland, Israel, Italy, Jamaica, Japan, Jersey, Jordan, Korea, South, Kuwait, Latvia, Liechtenstein, Lithuania, Luxembourg, Macau, Malaysia, Maldives, Malta, Martinique, Mexico, Monaco, Montserrat, Netherlands, New Zealand, Nicaragua, Norway, Oman, Pakistan, Panama, Paraguay, Peru, Philippines, Poland, Portugal, Qatar, Reunion, Romania, Saint Kitts-Nevis, Saint Lucia, Saudi Arabia, Singapore, Slovakia, Slovenia, South Africa, Spain, Sri Lanka, Sweden, Switzerland, Taiwan, Thailand, Trinidad and Tobago, Turks and Caicos Islands, United Arab Emirates, United Kingdom, United States, Uruguay, VietnamĪfghanistan, Albania, Algeria, American Samoa, Andorra, Angola, Anguilla, Argentina, Armenia, Azerbaijan Republic, Belarus, Benin, Bhutan, Bosnia and Herzegovina, Botswana, Burkina Faso, Burundi, Cameroon, Cape Verde Islands, Central African Republic, Chad, China, Comoros, Congo, Democratic Republic of the, Congo, Republic of the, Cook Islands, Côte d'Ivoire (Ivory Coast), Djibouti, Equatorial Guinea, Eritrea, Ethiopia, Falkland Islands (Islas Malvinas), Fiji, French Polynesia, Gabon Republic, Gambia, Georgia, Ghana, Guam, Guinea, Guinea-Bissau, Guyana, Haiti, India, Iraq, Kazakhstan, Kenya, Kiribati, Kyrgyzstan, Laos, Lebanon, Lesotho, Liberia, Libya, Madagascar, Malawi, Mali, Marshall Islands, Mauritania, Mauritius, Mayotte, Micronesia, Mongolia, Morocco, Mozambique, Namibia, Nauru, Nepal, Netherlands Antilles, New Caledonia, Niger, Nigeria, Niue, Palau, Papua New Guinea, Russian Federation, Rwanda, Saint Helena, Saint Vincent and the Grenadines, Senegal, Seychelles, Sierra Leone, Solomon Islands, Somalia, Suriname, Swaziland, Tajikistan, Tanzania, Togo, Tonga, Tunisia, Turkey, Turkmenistan, Tuvalu, Uganda, Ukraine, Uzbekistan, Vanuatu, Venezuela, Virgin Islands (U.S.), Wallis and Futuna, Western Sahara, Western Samoa, Yemen, Zambia, Zimbabwe While interfaces and appearances vary, all versions of Civilization Revolution feature the same content and run on the same rule set. A civilization can expand its territory by establishing new cities in unclaimed areas, or by taking over cities belonging to other nations.Maps are randomly generated for each game, and players can adjust various set-up and difficulty options. Food, research, and money are generated each turn, according to the types of terrain in the civilization's territory and the allocation of labor and infrastructure. Each turn, players make decisions about which technologies to research, what city improvements to build, how many military units to train and support, and whether to go to war or seek peace with competing civilizations. Civ vets will find simpler choices among such granular-level gameplay elements as tech tree advances, tile production, and military units, but the global-level influences of technology, economy, and armed forces interact with the same complexity as they do in other versions of the game.In Civilization Revolution, the player takes the role of an enduring, supremely powerful ruler, who leads a tribe of people from pre-historic beginnings through the ancient, medieval, industrial, and modern eras, to eventually become the most powerful nation on the planet (and perhaps even beyond). Developed from the ground up by Firaxis Games, Civilization Revolution aims to streamline the Civ experience without dumbing it down. Civilization may be the most archetypically "PC" game series in all of PC gaming, so significant adjustments were made in refitting it for Xbox 360, PS3, DS, and Wii. Players are invited to conquer the world in an afternoon, with the first version of Sid Meier's Civilization designed for consoles.
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The effects of significant DEGs and hub genes were verified and explored in other datasets. Then protein–protein interaction (PPI) networks were constructed to identify relevant hub genes and subnetworks. Enrichment analyses were conducted based on common DEGs among the three groups. Thereafter, the three groups’ differentially expressed genes (DEGs) were identified by comparing the gene data of the tumor groups with those of matched normal specimens. According to the tumor stage, GC gene chips were classified into three groups. Methods: Eligible microarray datasets were downloaded and integrated using the meta-analysis method. This study aims to identify the key genes and signaling pathways related to GC oncogenesis and progression using bioinformatics and meta-analysis methods. These findings suggested that members of the SLC1A family could be a potential target for the development of LUAD therapeutics as well as a reliable indicator of LUAD prognostic value.īackground : Owing to complex molecular mechanisms in gastric cancer (GC) oncogenesis and progression, existing biomarkers and therapeutic targets could not significantly improve diagnosis and prognosis. SLC1A family genes were involved in manifold biological processes and have different levels of DNA methylation and genetic alteration. Immune infiltration revealed a significant correlation between SLC1A family genes expression in LUAD. The ectopic expression of SLC1A family genes has prognostic value for LUAD patients. To study the expression and role of the SLC1A family in lung cancer, researchers used a variety of bioinformatics databases and tools.Īberrant expression of SLC1A family genes were demonstrated and analyzed the association with gender, tumor grade, cancer stages, and nodal metastasis status. This study aimed to explore the best biological understanding of SLC1A family in lung cancer. Specific functions of the SLC1A family in lung cancer are still not systematically described. The Solute Carrier 1A (SLC1A) family play a significant part in cellular biological process, inflammation, and immunity. Lung adenocarcinoma (LUAD) is the most common dangerous malignant tumor and the leading cause of global cancer incidence and mortality. SLC1A3 is therefore a potential therapeutic target in gastric cancer. Our findings indicate that SLC1A3 promotes gastric cancer progression via the PI3K/AKT signalling pathway. The PI3K/AKT inhibitor LY294002 prevented SLC1A3-induced glucose metabolism and cell proliferation. SLC1A3 overexpression activated the PI3K/AKT pathway and up-regulated GLUT1, HK II and LDHA expression. GSEA analysis suggested that SLC1A3 was positively associated with the up-regulation of the PI3K/AKT pathway. In vitro and in vivo assays showed that SLC1A3 affected glucose metabolism and promoted gastric cancer growth. SLC1A3 was found to be overexpressed in gastric cancer, and this overexpression was associated with poor prognosis. The roles of SLC1A3 in tumour growth were evaluated using a xenograft tumour growth model. Glucose consumption, lactate excretion and ATP levels were determined. SLC1A3 overexpressing and knock-down cell lines were constructed, and the cell viability was evaluated. The expression levels of SLC1A3 were examined using RT-qPCR and Western bolting. We used bioinformatics approaches to analyse the expression of SLC1A3 and its role in gastric cancer. The glutamate/aspartate transporter SLC1A3 has been implicated in tumour metabolism and progression, but the roles of SLC1A3 in gastric cancer remain unclear. Gastric cancer is a major cause of mortality worldwide. Seated in a row, with little production beyond some lighting, BTS gave a transcendent performance that left fans and non-fans alike with chills. 1 hit “Dynamite”).įor another, it had the rap line (RM, J-Hope and Suga) singing the lower harmonies to the vocal line’s melodies - an unusual but welcome occurrence for the group.īeyond that, “Fix You,” with its uplifting lyrics and soaring refrains, is a quintessentially BTS song that showcased the sheer magnificence of the group’s vocals and their desire to offer hope and comfort to their fans. The cover was notable for a couple of reasons: for one thing, it is only the second song that BTS have performed all in English (after their No. V, who originally wrote the song for his solo mixtape, said that he “tried to express my inner sadness and uncertainty, so I translated the feeling of burning out as ‘blue’ and the sadness of not being able to see ARMY as ‘grey.’”Īrguably the highlight of the concert, however, was BTS’s jaw-dropping, instantly-iconic cover of Coldplay’s “Fix You.” “Blue & Grey” offers a poignant insight into the burnout, depression and loneliness that even the most successful artists experience. With its simpler melody and light acoustic instrumentation, the track allows the group’s vocals to shine, especially V’s soulful baritone, which apparently has no concept of range. Like “Telepathy,” “Blue and Grey” is a B-side track off of “Be” that had never been performed live. Next on the set list was “Blue & Grey,” a melancholy guitar ballad that the group performed in a backlit, plant-filled greenhouse. Suga, who is performing again after taking time off for an injury, helped to write “Telepathy” and said that “the song’s lyrics describe our current situation of temporarily being apart from each other.” In true BTS fashion, the performance of “Telepathy” was an extravagant production of swooping camera shots and an ostentatious set that had the group members playing foosball and horsing around on a motorcycle in the background.īut despite its upbeat retro vibe and funky undertones, the lyrics, like those of most BTS songs, go deep. The concert opened with BTS’ first live performance of “Telepathy,” an exuberant disco-pop track off of “Be.” Calling the song “unplugged” might have been a bit of a stretch. The virtual concert, which featured four songs from “Be,” was a reminder to fans new and old of just how good BTS are, and will doubtless be remembered as one of their most iconic pandemic-era performances. 23, they continued to make history when they became the first K-pop group to perform on MTV’s legendary Unplugged series, joining the likes of Nirvana, Bruce Springsteen, Bon Jovi and Miley Cyrus. Undeterred, BTS began work on a brand-new, record-smashing album, “Be,” which was released in Nov. The group’s seven members - RM, Suga, J-Hope, Jin, Jimin, V and Jungkook - were prepping for a global tour of their penultimate album “Map of the Soul: 7” when the pandemic hit last March. The specific blend of insane chemistry, genre-bending music, angelic good looks, incredible stage presence and once-in-a-generation talent has made the K-pop group into a global phenomenon and earned them a literal army of devoted fans. The outfits were sold to two buyers, Japanese art collector Yusaku Maezawa and HIKAKIN, regarded as “Japan’s most famous YouTuber.There is no band in the world like BTS. BTS was also nominated for Best Pop Duo/Group Performance for the 63rd Grammy Awards, which will air on Sunday, March 14th.Įarlier this month, BTS auctioned off their outfit ensemble from the “Dynamite” music video for $162,500, which was donated to the MusiCares Covid-19 relief fund. In 2020, the group won VMAs for Best Pop, Best Group, Best K-Pop, and Best Choreography. RM, Jin, SUGA, j-hope, Jimin, V, and Jung Kook are scheduled to perform live from an intimate soundstage in Seoul, South Korea, and will play a number of their hits and songs from their latest chart-topping album BE, including “Dynamite” and “Life Goes On.”īTS released BE this past November. MTV Unplugged Presents: BTS will premiere exclusively on MTV in the U.S. The K-pop group join the ranks of Nirvana, Lauryn Hill and, more recently, Miley Cyrus as performers on the show. BTS are the latest artists to announce a set for MTV Unplugged, the long-standing MTV series that captures acoustic and semi-acoustic live performances from high-profile artists. Under no circumstances does this identification process provide us with personal information concerning you, nor does it give us access to the contents of your computer. For example, in order to check how many times the web site has been visited, what type of browser each user uses or to save the user from having to choose the language in which the web site appears every time he or she visits it. In order that the web site should work in an optimum fashion, it is sometimes necessary to obtain information from the computer or to identify it. 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We at ACT (Asociación clubes de traineras) are fully aware of how valuable your privacy is. Best Fitness Apps Of 2022įree for basic, $29.99 annually or $24.99 for six monthsįree for basic, PRO for $4.99 a month or $29.99 annuallyįree for basic, Elite for $12.99 a month or $69. And while it pumps up your device’s overall interface, it’s low on distraction and high on sophistication. This special set plays with positive & negative space to illustrate all your app icons to perfection. While we work hard to provide accurate and up-to-date information that we think you will find relevant, Forbes Health does not and cannot guarantee that any information provided is complete and makes no representations or warranties in connection thereto, nor to the accuracy or applicability thereof. Black & White Aesthetic App Icons Don’t underestimate the power of simple, subtle, & minimalistic line drawings. 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Black Icons Download 1385 Black Icons free Icons of all and for all, find the icon you need, save it to your favorites and download it free Toggle navigation. Read more > Blue Cedar BlackBerry Edition. Create your own feed of stories from the publications you know and trust. JOIN US ON OUR MISSION TO CHANGE THE GAME. With all of your black news in one place, it has never been easier to discover the stories that keep you informed, engaged, and inspired. Products supported by BlackBerry See More. Black® collects the news & stories from the world’s greatest influencers of black culture. The compensation we receive for those placements affects how and where advertisers’ offers appear on the site. The apps have been scanned by Veracode, functionally tested, and reviewed by a security team at BlackBerry. First, we provide paid placements to advertisers to present their offers. Focus on the conversation, automate note-taking, and collaborate faster with AI meeting assistant to transcribe, summarize, and analyze your meetings Meetings. They’re sleek, clean, and will never go out of style. Here are two ways you can turn off the notification: Select the Start button, then select Settings > System > Notifications & actions, and then turn off Display Settings. This compensation comes from two main sources. A black and white monochrome pack is a must-have for a minimalist enthusiast. While the notification for fixing blurry apps automatically can be useful, sometimes you might not want the notification to appear. To help support our reporting work, and to continue our ability to provide this content for free to our readers, we receive compensation from the companies that advertise on the Forbes Health site. The Forbes Health editorial team is independent and objective. While MyFitnessPal has a lot of positives, Weight Watchers offers the more complete and well-rounded approach to weight loss, in our opinion.Īs you’ll learn below, MyFitnessPal’s primary function is to help you log your food and activity each day. Why Some Say it’s Better Than MyFitnessPal The great thing about Weight Watchers is that they have several different plans to choose from, and while they all include the WW App, each one brings different features and pricing points, so there’s pretty much an option for everyone. Become Part of a Community: Connect in Person or on their Members-Only Social Network.Better Results with the New WW Freestyle Program.Use the WW Points to Track Food and Exercise.Pick Your Plan: Digital, Workshop and Digital, Personal Coaching and Digital.Here are the basics of how the new WW works: Weight Watchers changed things up recently, including a name change – they now go by WW, but even with some branding changes, much of the program has remained in tact. That means you can connect with other members, attend meetings, or even work one-on-one with a WW Coach to help you get your health on track, and even reach your weight loss goals. When you join WW, you become a part of a community. The all-new WW program is about much more than just weight loss, too. There’s a reason WW (Weight Watchers) is one of the most popular diets on the planet, and that’s because it has helped millions of folks lose weight ( read about our experience here). With that in mind, keep reading to learn more about both Weight Watchers and MyFitnessPal. In this Weight Watchers versus MyFitnessPal comparison, we’ll tell you everything you need to know about both of these diet programs, so you can decide which one is going to be the best one for you. If you’ve been looking for two great places to start, then you may want to check Weight Watchers or MyFintessPal.Įach of these diet apps brings their own set of features and options, so while Weight Watchers may work great for one person, MyFitnessPal may be the better options for another. Weight loss and diet apps are all the rage these days, but with so many options available, how can you possibly decide which one to go with? 3 Bottom Line: Which Diet App is Better?.1.2 Why Some Say it’s Better Than MyFitnessPal. *Please note that the eBook collection is hosted on a Third Party website with its own set of privacy policies. To copy a book to your eReader using Adobe Digital Editions, select the title and right click and copy to device, or drag and drop the eBook onto the device icon.Once your device is recognized, it should show up as an icon in the left-hand panel of Adobe Digital Editions in "Read" view. hi i have the adobe digital editions 4 and have recently purchased a kindle 6.Follow any instructions on your eReader's screen that say "Manage" or "Connect.".Experience a new ease-of-use as the books you. When comparing Adobe Digital Editions vs Amazon Kindle, the Slant community recommends Adobe Digital Editions for most people. Use it to download and purchase digital content, which can be read both online and offline. Download this free eReader to experience your books in the most optimum format across PC, MAC, tablets or mobile devices. Skip to Step 3 if you’ve already authorized your reader with your computer. 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NNELS: Talking Books for the Print Disabled.Libby/Library to Go: eBooks and eAudiobooks Getting started Adobe Digital Editions EPUB and PDF books Kindle for Mac Kindle format books OverDrive Media Console MP3 audiobook files cloudLibrary.formats including Adobe Digital Edition, Amazon Kindle and Apple iBook. Ebooks, Audiobooks and Digital Magazines SPE uses the free Adobe Digital Editions software to deliver its eBooks DIRECTLY. II! Although the players will be too tiny to play, they can have fun exploring some of the components.Īlthough this biome has been in the backyard since the beginning, players will experience a new Haze with this update. Something's abuzz over at the Picnic Table! Joining the beehive, players will now find trash from yesterday's lunch, along with the latest and greatest in tabletop RPGs, Minotaurs and Myrmidons vol. From food items in the knocked-over trash can to the AARTZ 3000, it'll be interesting to see what the players designate as treasure of their own. Too precious to throw away, but not precious enough for the Trash Heap! Here, players will be able to uncover some of the trash left in the backyard. This dungeon allows players to uncover new craftable weapons and armor, and includes a new mini-boss within its depths. Introducing a new sprawling anthill in the western yard full of black ants and other secrets. Either way, you'll have to discover new ways to survive while avoiding your new antlion friends! Thank you!ĭig up buried treasure and find ways to survive the sweltering heat of the Sandbox, or wait until night and venture forth in the dark. Please do not expect any new bases to work completely when moving over to a non-test build. We encourage players to build in these areas for feedback and testing purposes, but please keep in mind that the terrain and objects in these areas might shift or move before the official 0.11 release. Note for the test: The new areas are still in active development. After attending school in Brisbane he joined the RAAF in 1970 where he trained as an Aeronautical Engineer. Durham and emigrated with his family to Australia in 1961 at the age of 9. This biography shows that Roy was indeed a "Lucky Pommie Bastard"ĭon McNaughton was born in Darlington, Co. The life of immigrant "Pommie Bastards" in 1960's Australia and their acceptance, Aussie style, is explored through the experiences of Roy and his family through the eyes of the author. The experience of flying with an Australian squadron results in the Pommie gunner and his young family emigrating to Australia post war as 10 pound Poms. The life of a civilian, Roy's future wife, explores the trials and tribulations of wartime England. The experiences and fates of the crew are contrasted with those of RAF and RAAF aircrew mates who were mostly not so lucky. The Trimble crew survive numerous fighter attacks and accidents and with their tour of operations completed, move on to training roles and life after combat. The lives of aircrew on a Bomber Command squadron during 1943/44 are explored. Led by an Aussie pilot, Vic Trimble, the crew transfer in mid tour to 463 RAAF Lancaster squadron. The origins and experiences of the other Aussie and Brit crew members are explored during the same timeframe. The story follows the journey of a young Pommie gunner, Roy, the author's father, through volunteering for the RAF, training, joining a crew and then flying with 207 RAF Lancaster squadron. A biographical and social history of Bomber Command crews on operations at the height of the WW2 bomber offensive explored through the experiences of a surviving crew.Ī tale of Australians and Brits joining the RAAF and RAF and coming together to fly a tour of operations over Nazi occupied Europe and having the skills and luck to survive a full tour, including eight trips to Berlin. Inventors: Aharon Ofer (Givat Shmuel, IL), Goldberg Itzhack (Hadera, IL), Harony Shai (Kfar Sava, IL), Lechtman Moriel (Haifa, IL) Title: Highly miniaturized, battery operated, digital wireless camera using programmable single chip active pixel sensor (APS) digital camera chip (Pasadena, CA), Pain Bedabrata (Los Angeles, CA), Pasqualino Chris (Glendora, CA), Satorius Ed H. Title: Electrical funnel: a novel broadband signal combining method Inventors: Afshari Ehsan (Newfield, NY), Hajimiri Seyed Ali (Pasadena, CA) Title: Collaboratively locating disconnected clients and rogue access points in a wireless network Inventors: Adya Atul (Redmond, WA), Bahl Paramvir (Sammamish, WA), Chandra Ranveer (Kirkland, WA), Qiu Lili (Austin, TX) Title: Frameless radiosurgery treatment system and method (Stanford, CA), Schweikard Achim (Hamburg, DE) Inventors: Adekile Olusegun (Raleigh, NC), Silva Asima (Holden, MA), Wong Cesar A. Title: Context-based navigation through a database (Rutherfordton, NC), Friedlander Robert R. Title: System and method for dual speed passive optical networks Inventors: Adamiecki Andrew Larry (Morganville, NJ), Hadzic Ilija (Millington, NJ), Van Veen Doutje T. Title: Lipopeptides for delivery of nucleic acids Title: Multifunctional melamine epoxy resins, methylols and amines Inventors: Adam Georgius Abidal (Edensor Park, AU) Title: System and method for minimizing hardware and maximizing capacity in a wireless communications system Title: Multiple device shaping uniform distribution of current density in electro-static focusing systems (Huntington, NY), Levi Eli (Dix Hills, NY) Inventors: Abe Keisuke (Yokohama, JP), Kemmochi Kazuhisa (Suntou-gun, JP), Ida Hayato (Yokohama, JP), Hirasa Takashi (Yokohama, JP) Inventors: Abe Hiroyuki (Kanagawa, JP), Nagasawa Hironori (Kanagawa, JP) Inventors: Abe Hiroshi (Saitama, JP), Ito Yoshihiro (Tokyo, JP), Furukawa Kazuhiro (New Haven, CT) Inventors: Abdelli Said (Minneapolis, MN), Kriz Jeffrey (Eden Prairie, MN) Title: Software installation and configuration (Cairo, EG), Eissa Mahmoud (Cairo, EG), El-Shishiny Hisham E. |
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